Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVVKFGGSSLASGAQLDKVFHIVTSD-PARKAVVVSAPGKHYAEDTKVTDLLIACAEQYLA-T---GSAPELAEAVVERYALIANELQLGQSIIEKIRDDLFTLLEGD------KSNPEQYLDAVKASGEDNNAKLIAAYFRYKGVKAEYVNPKDAGLFVTNEPGNAQVLPESYQ-----NLYRLRERDGLIIFPGFFGFSK-DGDVITFSRSGSDITGSILANGLQADLYENFTDVDAVYSVNPSFVENPKEISELTYREMRELSYAGFSVFHDEALIPAFRAGIPVQIKNTNNPSAEGTRVVSKRDNTNGPVVGIASDTGFCSIYISKYLMNREIGFGRRALQILEEHGLTYEHVPSGIDDMTIILRQGQMDAATERSVIKRI---EEDLH-ADEVIVEHHLALIMVVGEAMRHNVGTTARAAKALSEAQVNIEMINQGSSEVSMMFGVKEAEERKAVQALYQEFFAGVLIS 2CDQ Chain:A ((28-486)) TCVMKFGGSSVASAERMKEVADLILTFPEESPVIVLSAMG-------KTTNNLLLAGEKAVSCGVSNASEIEELSIIKELHIRTVKELNIDPS---VILTYLEELEQLLKGIAMMKELTLRTRDYLVSFGECLSTRIFAAYLNTIGVKARQYDAFEIGFITTDDFTNGDILEATYPAVAKRLYDDWMHDPAVPIVTGFLGKGWKTGAVTTLGRGGSDLTATTIGKALGLKEIQVWKDVDGVLTCDPTIYKRATPVPYLTFDEAAELAYFGAQVLHPQSMRPAREGEIPVRVKNSYNPKAPGTIITKTRDMTKSILTSIVLKRNVTMLDIASTRMLGQVGFLAKVFSIFEELGISVDVVATSEVSISLTLDPSKLWS--RELIQQELDHVVEELEKIAVVNLLKGRAIISLIGNV-QHSSLILERAFHVLYTKGVNVQMISQGASKVNISFIVNEAEAEGCVQALHKSFFESG---

General information: TITO was launched using: RESULT: Template: 2CDQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2407 -254073 -105.56 -580.07 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -105.56 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.475

(partial model without unconserved sides chains): PDB file : Tito_2CDQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CDQ-query.scw PDB file : Tito_Scwrl_2CDQ.pdb: