Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLKKVILAAFILVGSTLGAFSFSSDASAKHVNGNITWYNGVGK-------KGSSGKKLGHWDC-AT----------KIGFDV-PRNGTKIRAYAKAKPKKVITVYKNDVGRMPNAVLDVSPKAFKALGYP---LSKGKVAGHYSY 4JP6 Chain:A ((5-117)) -----------------------------NVRATYHFYNAQQNGWDLRKVSAYCATWDADKPYSWRSKYGWTAFCGPVGPHGRAACGKCLRVTN-TKTRAETTVRIVDQCSNGG--LDLDWSVFKKLDTDGSGYLRGHLIVNYQF

General information: TITO was launched using: RESULT: Template: 4JP6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 384 -21136 -55.04 -232.26 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -55.04 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.418

(partial model without unconserved sides chains): PDB file : Tito_4JP6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JP6-query.scw PDB file : Tito_Scwrl_4JP6.pdb: