Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIDGVKVKKLMKHSDDRGFFAELVRDDENL------LEHFGQASWSKSYPGVIKAFHYHE---KQDDLWFFPTGHAQVVLYDLREDSKTKGETDVYYMGEDNPMLLLIPKGVAHGYRVLGETPLTIIYFTTMSYNPDQPDEKRIPWDDETIGFNWNTEFR 2C0Z Chain:A ((16-169)) GIEGVWEITPEQRADPRGVFLDWYHVDRFAEAIGRPL-RLAQANLSVSVRGVVRGIHFVDVPPGQAKYVTCVRGAVFDVVVDLRVGSPTYGCWEGTRLDDVSRRAVYLSEGIGHGFCAISD-EATLCYLSSGTYDPATE--HGVHPLDPELAIDWPTG--

General information: TITO was launched using: RESULT: Template: 2C0Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 713 -12230 -17.15 -84.34 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -17.15 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.437

(partial model without unconserved sides chains): PDB file : Tito_2C0Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2C0Z-query.scw PDB file : Tito_Scwrl_2C0Z.pdb: