Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRSNIRQLFYYIKPNLHYFIIA-FIAVLSSALTI---LLFGRGLSNIIDSGAE--HNFTTKLLVTIFIVLAI--SLTAFIRLYFIGIGSEKVIARIRYDLYGNITDLQPSFFEN--TSVQDVISALITDTSVLQSIMNSSLLTILRNFIILIGSVAMLLYTNLHLTTYAAAIIPMLLIIMTSLGKKVRNYARFAQNKL---SELASFSEENFRSIVTIKSFVLEENEKIRFKEHLDSVSKSYVKLVFLRAILVTLVIACVIGSLVILLFFGIKEVLSNNITVGEL---SSFVFYSALAAGTVNNLSDNISDLQRGFGIVERLFEFKNMKSSIMDV--DNPIKICGVKKGISFNGVTFFYESQPDKPALDNVSFSIETGQAVSIIGPSGSGKSTILKLLLRFHDPGKGSITIDGYNVKSIALSNLRSLFGLVPQDHIIFSCSIMENILYGKPG--AEYEEVRQAAISAYAMEFIEKLPDKFDTFVGKRGLKLSEGQKQRIIIARAILKNPQILILDEATSALDYKSENLVQKALSKLMQNRTTIMITHRLSTALKTDKVIVVNHGKVEEVGTHDSLMSKGGLYAKLTKI 4M2S Chain:B ((706-1263)) -----------------YFVVGIFCAIINGGLQPAFSVIFSKVVGVFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVV---SLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIE----KTPEIDSYSTQGLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSV

General information: TITO was launched using: RESULT: Template: 4M2S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -291143 for 3895 contacts (-74.7/contact) + 2D Compatibility (PS) -57804 + (NN) -31921 + (LL) 2028 1D Compatibility (HY) -36400 + (ID) 8800 Total energy: -424040.0 ( -108.87 by residue) QMean score : 0.453

(partial model without unconserved sides chains): PDB file : Tito_4M2S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4M2S-query.scw PDB file : Tito_Scwrl_4M2S.pdb: