Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKARGFKTKMRGFKIFSGSAHPAFGKEVSKHLGFPLSKAVIGKFSDGEINIQISESVRGKDIFIIQPTCVPVNDNLMELLVMVDALRRSSANSITAVLPYFGYARQDRKAAPRVPITAKMVANLMQEVGIERIITMDLHAGQIQGFFDVPVDNLYGSIVFRDYIRSK--ALKNPIIASPDVGGVTRARYFANQMGLDLIIVDKRREKANESEVMNIIGSAKERDVILVDDMIDTAGTICKAALALKEQGATSVMALGTHAVLSGNAIKRIKESALDEVVVTNSIPLVQK---CDKITTLSVASLFAEVIRRIYHNESVQSLFT 4F8E Chain:B ((3-314)) -----------NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEHVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKE-------DRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFS

General information: TITO was launched using: RESULT: Template: 4F8E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -277343 for 2577 contacts (-107.6/contact) + 2D Compatibility (PS) -33065 + (NN) -18867 + (LL) 1372 1D Compatibility (HY) -28000 + (ID) 7200 Total energy: -363103.0 ( -140.90 by residue) QMean score : 0.564

(partial model without unconserved sides chains): PDB file : Tito_4F8E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4F8E-query.scw PDB file : Tito_Scwrl_4F8E.pdb: