Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIYGIYMDRPLSQEENERFMSFISPEKREKCRRFYHKEDAHRTLLGDVLVRSVISRQYQ---LDKSDIRFSTQEYGKPCIPDL-PDAHFNISHSGRWVICAFDSQPIGIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQEGKGLSLPLDSFSVRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAAHPDFPEDITMVSYEELL 5CXD Chain:A ((26-116)) ----------------PKLVERILTKNEQHKFNNFTHEQRKIEFLAGRFATKEAFSKALGTGHVAFNDIDCYNDELGKPKIDYEGFIVHVSISHTEHYAMSQVV----------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5CXD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 293 -39971 -136.42 -475.85 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -136.42 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.503

(partial model without unconserved sides chains): PDB file : Tito_5CXD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CXD-query.scw PDB file : Tito_Scwrl_5CXD.pdb: