Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKAARWHNQ-KDIRIEHIEEPKTEPGKVKIKVKWCGICGSDLHEYLGGPIFIPVDKPHPLTNETAPVTMGHEFSGEVVEVGEGVENYKVGDRVVVEPIFATHGHQG----AYNLDEQMGFLGLA----GGGGGFSEYVSVDEE-LLFKLPDELSYEQGALV-EPSAVALYAVRS-S-KLKAGDKAAVFGCGPIGLLVIEALKAAGATDIYAVELSPERQQKAEELGAIIV-DPSKTDDVVAEIAERTG-GGVDVAFEVTGVPVVLRQAIQSTTIAGETVIVSIWEKGA-EIHPNDIVIKERTVKGIIGYR-DIFPAVLSLMKEGYFSADKLVTKKIVLDDLIEEGFGALIKEKSQVKILVRPN 3JV7 Chain:A ((1-345)) MKAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDIFVMDMPAAQ---------YAYGLPLTLGHEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGITPPGLGSPGSMAEYMIVDSARHLVPIG-DLDPVAAAPLTDAGLTPYHAISRVLPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVKSGAG--AADAIRELTGGQGATAVFDFVGAQSTIDTAQQVVAVDGHISVVGIHAGAHAKVGFFM-IPFGASVVTPYWGTRSELMEVVALARAGRLDI---HTETFTLDEGP-AAYRRLREGSIRGRGVVVP-

General information: TITO was launched using: RESULT: Template: 3JV7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1987 -216765 -109.09 -660.87 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -109.09 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.493

(partial model without unconserved sides chains): PDB file : Tito_3JV7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3JV7-query.scw PDB file : Tito_Scwrl_3JV7.pdb: