Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRYRTLLFDVDDTILDFQAAEALALRLLFEDQNIPLTND-MKAQYKTINQGLWRAFEEG---KMTRDEVVNTRFSALLKEYGYEAD---GALLEQKYRRFLEEGHQLIDGAFDLISNLQQQFDLYIVTNGVSHTQYKRLRDSGLFPFFKDIFVSEDTGFQKPMKEYFNYVFERIPQFSAEHTLIIGDSLTADIKGGQLAGLDTCWMNPDMKPN------VPEI-IPTYEIRKLEELYHILNIENTVSC 3UMG Chain:A ((13-250)) -RNVRAVLFDTFGTVVDWRTGIATAVADYAARHQLEVDAVAFADRWRARYQPSMDAILSGAREFVTLDILHRENLDFVLRESGIDPTNHDSGELD-ELARA-WHVLTPWPDSVPGLTAIKAEYIIGPLSNGNTSLLLDMAKNAGIP--WDVIIGSDINRKYKPDPQAYLRTAQVL-GLHPGEVMLAAAHN-GDLEAAHATGLATAFILRPVEHGPHQTDDLAPTGSWDISATDITDLAAQLRAGS----

General information: TITO was launched using: RESULT: Template: 3UMG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1192 -135138 -113.37 -603.29 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -113.37 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.505

(partial model without unconserved sides chains): PDB file : Tito_3UMG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UMG-query.scw PDB file : Tito_Scwrl_3UMG.pdb: