Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEIHTYEKEFFDLLKRISHYSEAVALMHWDSRTGAPKNGSEDRAESIGQLSTDIFN-----------IQTSDRMKELIDVLYERF-DDLSEDTKK----AVELAKKEYEENKK-----------IPEAEYKEYVI--LCSKAETAWEEAKGKSDFSLFSPYLEQLIEFNKRFITYWGYQEHPYDALLDLFEP------GVTVKVLDQLFAELKEAII----PLVKQVTASGNK-P------D-------------T----------SF------------ITKAFPKEKQKELSLYFLQELGYDFD-GG--------RLDETVHPFATTLN----RGDVRVTTRYDEKDFRTAIFGTIHECGHAIYEQNIDEALSGTNLSDGASMGIHESQSLFYENFIGRNKHFWTPYYKKIQEASPVQFKDISLDDFVRAINESKPSFIRVEADELTYPLHIIIRYEIEKAIFSNEVSVEDLPSLWNQKYQDYLGITPQTDA----EGILQDVHWAGGDFGYFPSYALGYMYAAQLKQKMLEDLP---EFDALLERGEFHPIKQWLTEKVHIHGKRKKPLDIIKDATGE-ELNVRYLIDYLSNKYSNLYLL 1R42 Chain:A ((24-593)) ----QAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEV-GKQLRPLYEEYVVLKNEMARANHY-EDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKV--TMDDFLTAHHEMGHIQYDMAYAA--QPFLLRNGANEGFHEAVGEIMSLS-AATPKHLKSIGL-LSPDFQ-------EDN-ETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSN--DYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDI-SNSTEAGQKLF-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFT-----

General information: TITO was launched using: RESULT: Template: 1R42.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1806 36357 20.13 77.68 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 20.13 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.435

(partial model without unconserved sides chains): PDB file : Tito_1R42.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1R42-query.scw PDB file : Tito_Scwrl_1R42.pdb: