Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMEKTFIMVKPDGVQRQLIGDILSRFERKGLQLAGAKLMRVTEQMAEKHYAEHQGKPFFGELVEFITSGPVFAMVWEGENVIEVTRQLIGKTNPKEALPGTIRGDYGMFVGKNIIHGSDSLESAEREINIFFKNEELVSYQQLMAGWIY 3Q8U Chain:B ((1-148)) -MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMELAETHYGEHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGSIRGDLGLTVGRNIIHGSDSLESAEREINLWFNENEITSYASPRDAWLY

General information: TITO was launched using: RESULT: Template: 3Q8U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 690 -66859 -96.90 -451.75 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.93 3D Compatibility (PKB) : -96.90 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.93 QMean score : 0.546

(partial model without unconserved sides chains): PDB file : Tito_3Q8U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3Q8U-query.scw PDB file : Tito_Scwrl_3Q8U.pdb: