Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNEMHLEFSALSQNESFARVTVASFIAQLDPTMDELTEIKTVVSEAVTNAIIHGYEENCEGKVYISVT-LEDHVVYMTIRDEGLGITDLEEARQPLFTTKPELERSGMGFTIMENFMDDVSIDSSPEMGTTIRLTKHLSKSKALCN 3KE6 Chain:A ((262-389)) ---PLHITLDATINAARTVRAQLREWLAEIGADHSDIADIVHAISEFVENAVEHGYATDVSKGIVVAAALAGDGNVRASVIDRGQW-----------------------GLAMAEALVSEARIMHGA-GGTTATLTHRLSRPA----

General information: TITO was launched using: RESULT: Template: 3KE6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 569 -48578 -85.37 -422.41 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -85.37 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.352

(partial model without unconserved sides chains): PDB file : Tito_3KE6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3KE6-query.scw PDB file : Tito_Scwrl_3KE6.pdb: