Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELYECIQDIFGGL--KNPSVKDLATSLKQIPNAAKLSQP--YIKEPDQYAYGRNAIYR--NNELEIIVINIPPNKETTVHDHGQSIGCAMVLEGKLLNSIYRSTGE--HAELSNSYFVHEGECLISTK--GLIHKMSNPTS-ERMVSLHVYSPPLEDM--TVFEEQKEVLENS 4WVZ Chain:A ((11-174)) RQFIGELATLLDSRPDESTLLAQAHPLLAELV-HQDDWLPEDCARPDPQR-YQQYLLHVDSRQRFSVVSFVWGPGQITPVHDHR-VWCLIGMLRGAEYSQPYAFDAGGRPHPSGARRRLEPGEVEALSPRIGDVHQVSNAFSDRTSISIHVYGANIGAVRRAVFSAE-------

General information: TITO was launched using: RESULT: Template: 4WVZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 707 4948 7.00 32.76 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 7.00 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.510

(partial model without unconserved sides chains): PDB file : Tito_4WVZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4WVZ-query.scw PDB file : Tito_Scwrl_4WVZ.pdb: