Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSRHWPLFDLRITTPRLQLQLPTEELCDQLIDTILEGVHDPDRMPFSVPWTRASREDLPFNTLSHLWQQLAGFKRDDWSLPLAVLVDGRAVGVQALSSKDFPITRQVDSGSWLGLRYQGHGYGTEMRAAVLYFAFAELEAQVATSRSFVDNPASIAVSRRNGYRDNGLDRVAR---EGAMAEALLFRLTRDDWQ-RHRTVEVRVDGFDRCRPLFGPLEPPRY 2Z10 Chain:A ((4-185)) -------FPERFEGRHVRLEPLALAHLPAFLRHY-----DPEVYRFLSRAPVAPTEEALRAHLEGLL-------GEPGRVNWAILFGKEVAGRISVIAPE-PEHAKLELGTMLFKPFWGSPANKEAK-LLLRHAFEVLRAERVQFKVDLRNERSQRALEALGAVREGVLRKNRRLPDGAFRDDVVYSVLKEEWPGVKARLEA--------------------

General information: TITO was launched using: RESULT: Template: 2Z10.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -57255 for 1317 contacts (-43.5/contact) + 2D Compatibility (PS) -18370 + (NN) -6506 + (LL) 2124 1D Compatibility (HY) -5200 + (ID) 1650 Total energy: -86857.0 ( -65.95 by residue) QMean score : 0.313

(partial model without unconserved sides chains): PDB file : Tito_2Z10.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Z10-query.scw PDB file : Tito_Scwrl_2Z10.pdb: