Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQVLAKENIKLNQTVSSKEEAIKLAGQTLIDNGYVTEDYISKMFEREET-SS-TFMGNFIAIPHGTEEAKSE-VLHSGISIIQIPEGVEYGE-GNTAKVVFGIAGKNN-EHLDILSNIAIICSEEENIERLISAKSEEDLIAIFNEVN 2OQ3 Chain:A ((5-146)) -DYFPESSISVIHSAKDWQEAIDFSMVSLLDKNYISENYIQAIKDSTINNGPYYILAPGVAMPHARPE---CGALKTGMSLTLLEQGVYFPGNDEPIKLLIGLSAADADSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISR--

General information: TITO was launched using: RESULT: Template: 2OQ3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 696 -94559 -135.86 -690.21 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -135.86 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.569

(partial model without unconserved sides chains): PDB file : Tito_2OQ3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OQ3-query.scw PDB file : Tito_Scwrl_2OQ3.pdb: