Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAVCLVRHGETDWNLQQKCQGK-TDIPLNATGERQARETGEYVKDFSWDIIVTSPLKRAKRTAEIINEYLH----LPIVEMDDFKERDYGDAEGMPLEERTKRYPD-------NIYPNMETLEELTDRLMGGLAKVNQA-----------------------YPNKKVLIVAHGAAIHALLTEISGGDPE-L--------QSTRLVNACLSNIEFAE--E---KW--RIKDYNINSHLSGFIK 3DCY Chain:A ((8-269)) RFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKNCLETSLAEIFPLIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIINFEEGREVKPTVQCICMNLQDHLN----

General information: TITO was launched using: RESULT: Template: 3DCY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1004 -69931 -69.65 -370.01 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -69.65 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.429

(partial model without unconserved sides chains): PDB file : Tito_3DCY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DCY-query.scw PDB file : Tito_Scwrl_3DCY.pdb: