Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVRFLQISDLHFQFQNYD------TIVMRDKLLDFIEVLRRESDFDFLLLTGDIAHKGDVYNEDVKEYLNGIIKSMGLSKNNVHLVPGNHDISRDMTRTLLIDSIMKSPNPSEMLDKLDQKATNILVEGQRKFFDFYEDFMGVKYPEEDLHFL--YQSEKYNVLSINTCLLSDKKG-EEGT---LLTAQMKLYKAIRKMNKEK---NKGKVLNIAIGHHTLGCIESS--ERE-------SIKAHFDDYFIDLYLAGHVHDSSFNITANTNENPFLELVSGAIIKD---EY-ATPEFISVDVNLDNGETEVTYYIWNTEYKYWSKNNQGGRRLQEGKLNYKINRLESLIEKEIEDNDDKIDEDEFKSFIIDFHEYRESYKTFTSNFDNQIGLDKKFYDMKSGETFKRKFDSYSEYFGVINHIMDSTSYVSADKKELIAETIVDKYLEFHNQYNNGDEIFVKIVNEIYLECHSVLPYSKALTKKYIKILTCWCIYECEIFNDNKRSVKND 4LTY Chain:C ((13-284)) EFMRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQ----THQVDAIIVAGDVFDTGSPPS-YARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESR------------------------DIMA-FLNT--TV--VASAG--HAPQILPRRDGTPGAVLCPIPFLRPRDIITSQ---EKQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFP-AQNFPPADYIALGHIHRAQIIG------GMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4LTY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1184 21970 18.56 95.11 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain C : 0.60 3D Compatibility (PKB) : 18.56 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.379

(partial model without unconserved sides chains): PDB file : Tito_4LTY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LTY-query.scw PDB file : Tito_Scwrl_4LTY.pdb: