Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIK-EIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG-DKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS 4O27 Chain:B ((12-247)) -------------------------------------EKIGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-----EPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNEFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPK----NNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTS

General information: TITO was launched using: RESULT: Template: 4O27.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -98195 for 1809 contacts (-54.3/contact) + 2D Compatibility (PS) -25069 + (NN) -17357 + (LL) 2932 1D Compatibility (HY) -19200 + (ID) 3950 Total energy: -160839.0 ( -88.91 by residue) QMean score : 0.474

(partial model without unconserved sides chains): PDB file : Tito_4O27.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4O27-query.scw PDB file : Tito_Scwrl_4O27.pdb: