Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQKQSKSVAIWLFLCSIMIVLMVGIGGFTRLSKAGLSITEWNPITGAFPPLNERDWLQEKSKYETTPEYKTFNYGMSMEEFRTLYLIEYVHRLFARLTGLIFILPFIYFTLKKRISKKVVIRLSIALSFGVLQAFTGWYMVKSGLVAKPHVSHYMLTLHLLLALVIFALLSYQFFNYQVRQKQTKLKISGSTVHYVGIILILIVVQIIFGAFVAGLNAGLIYNTFPLMGGHIIPKDLFFLQPTWLNIFENRATVQFIHRTLALLILVLTTVLTIKNASVKSVYVMLLSVIIQIILGVVTLLLHIPITIAISHQMFSFILFGSGLCFLCYLRKQN 1DML Chain:B ((1200-1235)) ----------------------------------------------------------DDVAARLRAAGFGAVGAGATAEETRRMLHRAFDTLA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1DML.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -1397 for 165 contacts (-8.5/contact) + 2D Compatibility (PS) -3876 + (NN) -1432 + (LL) 28628 1D Compatibility (HY) 1600 + (ID) 200 Total energy: 23323.0 ( 141.35 by residue) QMean score : 0.298

(partial model without unconserved sides chains): PDB file : Tito_1DML.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DML-query.scw PDB file : Tito_Scwrl_1DML.pdb: