Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAFEDIPFLQYLGNAVDILLVW----YVIYKLIMVIRGTKAVQLLK-------------------GIVVI----VLVRMASQYLGLSTLQWLMDQ--------------------------AITWGFLAIIIIFQPELRRALEQLGRGRFFSRSGTPVEEAQQKTIEAITKAINYMAKRRIGALLTIERDTGMGDYIETGIPLNA--------KVSSELLINIFIP-----NTPLHDGAVIMKNNEIAAAACYLPLSESPFISKELGTRHRAAVGISEVTDSLTIIVSEETGGVSV----AKNGDLHRELTEEALKEMLEAEFKKNTRDTSSNRWYWRGKKNG------------------------------------------------- 3MS5 Chain:A ((1-385)) SMACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGAS---DKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYC----DFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE

General information: TITO was launched using: RESULT: Template: 3MS5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -95344 for 1661 contacts (-57.4/contact) + 2D Compatibility (PS) -29046 + (NN) -7689 + (LL) 708 1D Compatibility (HY) -8000 + (ID) 1550 Total energy: -140921.0 ( -84.84 by residue) QMean score : 0.133

(partial model without unconserved sides chains): PDB file : Tito_3MS5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MS5-query.scw PDB file : Tito_Scwrl_3MS5.pdb: