Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDFEKIRKWLEITNEYKQSDFWTNVLKYKAPEHFFDSEASTFVYDFYQDEEYNFIIVEMPGVYEEELTIRLLSKTQLLIKGTITPVFPAEMEVLRERYYGEIERIIQLPEAAETHLLQIQL-LNGLLHISYPRQVETVAFNKGL 3L1E Chain:A ((2-92)) ----------------------------------------SGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQE-DFVEIHGKHNERQDDHGY-----ISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKIPSG-------

General information: TITO was launched using: RESULT: Template: 3L1E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 342 -52764 -154.28 -586.27 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -154.28 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.345

(partial model without unconserved sides chains): PDB file : Tito_3L1E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3L1E-query.scw PDB file : Tito_Scwrl_3L1E.pdb: