Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQPLVGIIMGSTSDWETMKHACDILDELNVPYEKKVVSAHRTPDFMFEYAETARERGIKVIIAGAGGAAHLPGMTAAKTTLPVIGVPVQSKALNGMDSLLSIVQMPGGVPVATTSIGKAGAVNAGLLAAQILSAFDEDLARKLDERRENTKQTVLESSDQLV 3LP6 Chain:D ((7-146)) -RPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVSAHRTPEAMFSYARGAAARGLEVIIAGAGGAAHLPGMVAAATPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAG--NAGLLAVRMLGAANPQLRARI-------------------

General information: TITO was launched using: RESULT: Template: 3LP6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 805 -126479 -157.12 -903.42 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain D : 0.86 3D Compatibility (PKB) : -157.12 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.603

(partial model without unconserved sides chains): PDB file : Tito_3LP6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LP6-query.scw PDB file : Tito_Scwrl_3LP6.pdb: