Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----------MSFFKKLAASAGIGAAKVDTILEKDAYFPGEEVQGTVHVKGGKIAQDIRYID---LQLSTRYVIVKDDEEHRKYATIHSFRVTGSFTIQPGEEHQFPFTFTLPLDTPITVGKVEVAVVTDLDIQGGIDKSDHDRIFVEAHPWIENVLEAIENLGFRLNEADCEQAPYFQRRLPFVQEFEFVPTSGYYRQMLDELELIFLLDEDGLEIIFEVDRRAR--GLRGWLEEMYNDGEQLVRVRFSQSELEDTEELEEVLEEILDQYAE 1QTS Chain:A ((692-938)) GSPGIRLGSSEDNFARFVCKN-----N--GVLFEN---QLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICADDLQTNLNLQTKPVD--PTVDGG--AQVQQVVNIECISDFT----EAPVLNIQFRYGGTFQNVSVKLPITLNKFFQP-TEMASQDFFQRWKQLSNPQQEVQNIFKAKHPMDTEITKAKIIGF--GSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKDTVSQRLCELLSEQF-----

General information: TITO was launched using: RESULT: Template: 1QTS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1190 -90758 -76.27 -391.20 target 2D structure prediction score : 0.41 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -76.27 2D Compatibility (Sec. Struct. Predict.) : 0.41 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.303

(partial model without unconserved sides chains): PDB file : Tito_1QTS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QTS-query.scw PDB file : Tito_Scwrl_1QTS.pdb: