Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------MSLNQKALNSYVYTLAFSSLSFGLIFGLY-----LFVYSGFMAIALVT-IAIIAFYALITYLVFAAPLQVWLRRRRRKFSL-----INFLIYIAVAFSA---VFLFWFVDYPPNALTMFRSFEYYIMSIVAAFIYWFWDSIFLRN 1YQ5 Chain:A ((197-340)) GGVTDALSLMYSTSTGGPASIAANALTDFDLSGALTVNSVGT--GLTKSAAGIQLAAGKSGLYQITMTVKNNTVTTGNYLLRVKYGSSDFVVACPASSLTAGGTISLLIYCNVLGVVSLDVLKFSLCNDGA-------ALSNYIINITAAKIN----------

General information: TITO was launched using: RESULT: Template: 1YQ5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 406 -63684 -156.86 -568.60 target 2D structure prediction score : 0.07 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -156.86 2D Compatibility (Sec. Struct. Predict.) : 0.07 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.050

(partial model without unconserved sides chains): PDB file : Tito_1YQ5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YQ5-query.scw PDB file : Tito_Scwrl_1YQ5.pdb: