Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNKWKRLFFILLAINFILAAGFVALVLLPGEQAQVKDASESEYGFQVTSTKE---SLAAFVNSYLNDKASNKLDYKVEIDDDVHVAGK------IKAFSTSIDAFIAFEPTVKKNGDV-ELNVTKFSLGKLSIPIS------------FVLNYMDSFYELPSFVHVHPGDKS----IEVRLSEMPLTNGMYVKA---------------DKINLEKDEIEFSYYHPKQ------------------------------------ 3TUR Chain:A ((29-286)) ---HLTMPYVMPGDGEVVGVGEPVAIRFDEN---IADRGAAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAK

General information: TITO was launched using: RESULT: Template: 3TUR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 734 5265 7.17 29.09 target 2D structure prediction score : 0.35 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 7.17 2D Compatibility (Sec. Struct. Predict.) : 0.35 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.110

(partial model without unconserved sides chains): PDB file : Tito_3TUR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TUR-query.scw PDB file : Tito_Scwrl_3TUR.pdb: