Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQQLTFYSYPSCTSCRKTKHWLKAHQIEFNERHLFRETPTREELKYILSLTTEGIDEILATRSQTFKNLNLNI--EEMTVNEVLELLIEKPKLLRRPILVDNKKLVIGYNPGELLKLSKKKTVHQSA 2M46 Chain:A ((1-117)) ---MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWL--------

General information: TITO was launched using: RESULT: Template: 2M46.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 475 -11901 -25.05 -103.49 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -25.05 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.550

(partial model without unconserved sides chains): PDB file : Tito_2M46.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2M46-query.scw PDB file : Tito_Scwrl_2M46.pdb: