Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------MNWVPSMRKLSDELLIESYFKATEMNLNRDFIELIENEIKRRSLGHIISVSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1O57 Chain:A ((2-276)) KFRRSGRLVDLTNYLLTHPHELIPLTFFSERYESAKSSISED-LTIIKQTFEQQGIGTLLTVPGAAGGVKYIPKMKQAEAEEFVQTLGQSLANPERILPGGYVYLTDILGKPSVLSKVGKLFASVFAEREIDVVMTVATKGIPLAYAAASYLNVPVVIVRKDGSTVSINYVSGSSNRIQTMSLAKRSMKTGSNVLIIDDFMKAGGTINGMINLLDEFNANVAGIGVLVEAEGVDERLVDEYMSLLTLSTINMKEKSIEIQNGNFLRFFKDN

General information: TITO was launched using: RESULT: Template: 1O57.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 121 -422 -3.48 -8.26 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.52 3D Compatibility (PKB) : -3.48 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.52 QMean score : 0.236

(partial model without unconserved sides chains): PDB file : Tito_1O57.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1O57-query.scw PDB file : Tito_Scwrl_1O57.pdb: