Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKNSKAIGNNHVKSVYQALLQSLKSKSVNGFSKITIETISFIKNLYPEIDSVTSKFDNSRPDQSKDLTLYLKSGETISLNLFLIKKGRRIQPKNAGAKSFLEKYFLSAEMQKIFNKE-----FE-----RYYLDYLKEVVEHKKGTHYITDKRELKRLVSSHFPKFTEEINLYRDKFLFNLRETCFTLLQQFYNEKNIGFTHAFNVFFMVNDTNIITSYGKDENDVKVEKFAPASPSLKDIELYKTGKSTVGIKFGEVGLTLRFKFESDPWKSIKLATGYHEFPKEKERVNVNLK---TMRRMEKLLNKHEYAKTSNNSNAIGKCHEAWTYYYFLKAFPDVIQVDPKQCVELINTYFSSINQNTLKKLYSSTSTIVDAITEKLRQKYHDYIIESIELIPDAYIKDRLDTGDLQLVLKVNNNIIVENISLKALAKRNSKITTKNPGMGSILGPTYFNMGSMESVINEVKNKFTIGEFNHRKSLEILSYEFGMKLDSATQEQLRRGIHNLLGKAMIAITIYGEGISFCKEPSEIDGEVKVHVNVPSAIQNTLTWNNELESISLRAKFSKSQKHGWSSIKLTSECQLESRK 4PG7 Chain:A ((20-446)) -----------HMKKLNIALL-----------------------GLGTVGSGVVKIIEENRQQIQDTL------NKDIVIKHILVRDKSKKRPLN------ISQYHLTEDVNEILNDDSLDIIVEVMGGIEPTVDWLRTALKNKK--HVITANKDLLAVHLKLLEDLAEENGV-------ALKFEASVAGGPNNISKFMGILNGTSNFILSKMTKEQTTFEEALDEAKRLGFAEADP-TDDVEGVDAARKVVITSYLSFNQVI--KLNDVKRRGISGVT--------LTDINVADQLGYKIKLIGKGIYENGKVNASVEPTLIDKKHQLAA-------------------VEDEYNAIYVIGDAVGDTMFYGKGAGSLATGSAVVSDLLNVALFFESTLPPHF---ELKTDKTREMEKSNFFVVVNHVK-----------------------------GSIENFENELKAILP-----FHRSLRVANYD----------------------NQSYAAVIVG-----------------------------------LES-SPEELITK---HGY---EVDKVYPVEGV-

General information: TITO was launched using: RESULT: Template: 4PG7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1960 19074 9.73 49.03 target 2D structure prediction score : 0.42 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 9.73 2D Compatibility (Sec. Struct. Predict.) : 0.42 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.226

(partial model without unconserved sides chains): PDB file : Tito_4PG7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4PG7-query.scw PDB file : Tito_Scwrl_4PG7.pdb: