Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNILL--VCAAGMSTSLLV-SKMEKSAQEQGKDYTIWAVSGDSVQN-----HIDKADVLLLGPQVRYMLPQLKKLGESKGVPVDVINTVHYGTCNGAEVLKSAEQLGHVS 2M1Z Chain:A ((3-105)) RKIIAVTACATGVAHTYMAAQALKKGAKKMGNLIKVETQGATGIENELTEKDVNIGEVVIFAVDTKVR--N-KERF--DGKVVLEVPVSA-PIKDAEKVINAALALIDE-

General information: TITO was launched using: RESULT: Template: 2M1Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 486 -1868 -3.84 -19.66 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -3.84 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.581

(partial model without unconserved sides chains): PDB file : Tito_2M1Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2M1Z-query.scw PDB file : Tito_Scwrl_2M1Z.pdb: