Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRLLVLFCCLWLLPGVASAAPSVGEIRVVSETWTRYTQEDGRGVAWDLLRAVYEPAGVRLRIANEP-YTRAVGLVLRGEADAWV-GAYRGEIDE--ALYPRWPYDVDPIAVLSLKDN-PPPPLEGLSRFRLSWMRGYAFARYFPT-LTPHSELQRRTSALPMLLNHRVDYFIDSRPELEEMLAGAGALAAEYRI--TDVTRLPLYLGFSDSPRGRELLALFDRRMRQLHASGELERIFARWNWPYAPLKAILPPKE 2PYY Chain:A ((4-223)) ------------------------PLLVATRVIPPFVLSNLSGFSIDLWRSIATQIGIESKLIEYSSVPELISAIKDNKVNLGIAAISITAEREQNFDFSL-PIFASGLQIMVRN--GDIRSIDDLPGKVVATTAGSTAATYLREHHISVLEVPKIEEAYKALQTKKADAVVFDAPVLLFYAANEG--KGKVEIVGSILREESYGIILPNN---SPYRKPINQALLNLKENGTYQSLYDKWFDP------------

General information: TITO was launched using: RESULT: Template: 2PYY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -126984 for 1649 contacts (-77.0/contact) + 2D Compatibility (PS) -22891 + (NN) -14916 + (LL) 2948 1D Compatibility (HY) -7600 + (ID) 1250 Total energy: -170693.0 ( -103.51 by residue) QMean score : 0.341

(partial model without unconserved sides chains): PDB file : Tito_2PYY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2PYY-query.scw PDB file : Tito_Scwrl_2PYY.pdb: