Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQ--EGSQGDIALLQLSRPITFSRYIRPICLPAANA---SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH 2WPH Chain:S ((1-233)) --------------------------------------------VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVET---GVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNFNAAINTYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGS-GYVSGWGRVFHKGR--SALVLQYLRVPLVDRATCLRSTKF--------TITNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK---------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2WPH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -165060 for 1975 contacts (-83.6/contact) + 2D Compatibility (PS) -25019 + (NN) -9916 + (LL) 6260 1D Compatibility (HY) -16000 + (ID) 4400 Total energy: -214135.0 ( -108.42 by residue) QMean score : 0.326

(partial model without unconserved sides chains): PDB file : Tito_2WPH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WPH-query.scw PDB file : Tito_Scwrl_2WPH.pdb: