Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKLLRKPLNERIAPGVTLVQDINQGNSPLSYVGFRLIELEEDAVYQETLDGLECCIVALTGKISVSEGD----HVFSEIGTRANVFEKIPTDSVFISGGRAFQVKADA--EKARVALCYSPADRNLPTTLIKASDNSIEQRGKYQNKRLVHNILPDVSEVASSLLVVEVYTDGGNFSSYPPHKHDHDNLPAESLLEESYYHEINPKQGFIFQRVYTDDRALDETMAVEHQNAVIVPEGYHPVGVPDGYDSYYLNVMAGPKRVWEFHNDPDHEWILERD 2CAV Chain:A ((84-195)) ------------------------------RDYRVLEYCSKPNTLLLPHHSDSDLLVLVLEGQAILVLVNPDGRDTY-K-------LDQ--GDAIKIQAGTPFYLINPDNNQNLRILKFAI--------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2CAV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -47112 for 488 contacts (-96.5/contact) + 2D Compatibility (PS) -8000 + (NN) 1120 + (LL) 9992 1D Compatibility (HY) -3600 + (ID) 350 Total energy: -47950.0 ( -98.26 by residue) QMean score : 0.424

(partial model without unconserved sides chains): PDB file : Tito_2CAV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CAV-query.scw PDB file : Tito_Scwrl_2CAV.pdb: