Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNDQSCVRIMTEWDIVAARQLGRNVAKELGFGTVDQARITTAISELARNIYLYAG-KGQIGIEQVADRGKKGLKIIAEDQGPGIPD--IRKVMEDGFST----SGGLGAGLPGVKRLMDE----FSLNSVAGEGTEIQAIKWLR 4I5S Chain:A ((319-432)) -----------------------------VWIEIDTDKMTQVIDNILNNAIKYSPDGGKVTITMQT--TDTQLILSISDQGLGIPKKDLPLIFDRFYRVDKAR----GLGLAIAKEIVKQHKGFIWANSEEGEGSTFTIVLP--

General information: TITO was launched using: RESULT: Template: 4I5S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 401 -39550 -98.63 -411.97 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -98.63 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.466

(partial model without unconserved sides chains): PDB file : Tito_4I5S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4I5S-query.scw PDB file : Tito_Scwrl_4I5S.pdb: