Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVTRITGLASGMDIDDIVSKLMQTERAPLDKLTQKKQTLEWQRDSYREVNSKIKELQDYMSKNTLTYPSTYQSKTVTSSNESVLTATGSVSAPNSSSTVEVASLATAATYKANNYTGYTQGDYNLAFNVVAPGETTAKTVNISVTSADTIDNVISKLNSSDLGVSAFKDKIWNGTEYVETIAFSSKATGAGGSIQAADSATADFMSGQLGFSLDADNKLTAYKEGTNAKVTINGFEMEKLTNNFTVNGVTYSIKNTTAATGPVTTSVSTDVDGIYNQIKEFVDKYNELVDSLNEKLKEEKYRDYTPLTSEQKEAMSDKEVELWEEKAKSGLLRNDSSISTGTNQMRTDFYTQVNADGKTYQLTEFGITTSSAYQLRGHLEINEEKLKAKIAEDPQGVANLFTSGTNDSNYSDKGIMKRITNTLRSTVKSIEAKAGNSTMGASSYSIGKNLNSISTEITDMQDRLNTIEN--RYYSKFSAMDSAIQKMNEQASYLSQLLVQ--- 4O5J Chain:A ((27-400)) --------------LKNLNEKYEQLSQYLNQVASLKQSIQNANN-IELVNSSLNYLKSFTNNNYNS---------------------TTQSPIFNAVQAVITSVLGFWSLYAGNYFTFFVG------KKVDSGQPASVQGNPPF---KTIIENCSGIENCAMDQTTY-DKMKKLAEDLQAAQTNSATKGNNLCALSGCAATSNPPNSTVSNALNLAQQLMDLIANTKTAMMWKNIVISGVSNT----------------SGAITSTNYPTQYAVFNNIKAMIPILQQAVTLSQSNHTLSA--------SLQAQATGSQTNPKFAKDIYT-FAQNQKQVISYAQDIFNLFNS---IPAEQYKYLE-----------------------------------------------------------KAYLKIPNAGSTPTNPYRQVVNLNQEVQTIKNNVSYYGNRVDAALSVARDVYNLKSNQAEIVTAYNDAKTLSEEISKLPH

General information: TITO was launched using: RESULT: Template: 4O5J.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1706 -30344 -17.79 -83.13 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -17.79 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.186

(partial model without unconserved sides chains): PDB file : Tito_4O5J.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4O5J-query.scw PDB file : Tito_Scwrl_4O5J.pdb: