Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKNEILWGIAPIGWRNDDMPEIGAGNTLQHLLSDIVVARFQGTEVGGF-FP--EPAILNKELKLRNLRIAGKWFSSFILRDG---LGEAAKTFTLHCEYLQQVNADVAVVSEQTYSVQSLEKNVFTEKPHFTDDEWERLCEGLNHLGEIAAQHGLKLVYHHHLG------TGVQTAEEVDRLMAGTDPAHVHLLYDTGHAYISDGDYMGMLEKHIG--RIKHVHFKDARLNVMEQCRLEGQSFRQSFLKGMFTVPGDGCIDFREVYQLLLKHSYSGWIVIEAEQDPD-V-ANPLEYALIARNYIDQQLLDLA 3QC0 Chain:A ((2-274)) --MQVEGLSINLATIR--------EQCGFAEAVDICLKHGITAIAPWRDQVAAIGLGEAGRIVRANGLKLTGLCRGGFFPAPDASGREKAIDDNRRAVDEAAELGADCLVLVAGGL----------PGGSKNIDAARRMVVEGIAAVLPHARAAGVPLAIEPLHPMYAADRACVNTLGQALDICETLG-PGVGVAIDVYHVWWDP-DLANQIARAGKMKAILAHHICDWLVPTKD-------------MLTDRGMMGDGVIDLKGIRRRIEAAGFHGAQEVEIFSADNWWKRPADEVIATCVERYRNC-----

General information: TITO was launched using: RESULT: Template: 3QC0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1432 -31372 -21.91 -122.07 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -21.91 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_3QC0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QC0-query.scw PDB file : Tito_Scwrl_3QC0.pdb: