Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVE--RWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYD-PEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE- 4D6W Chain:A ((1-415)) --YLSIAFPENTKLDWKPVTKNTRYCPPGLQEESFLSSTPIGATPSKSD---------------------------GFLCHAAKWVTTCDFRWYGPKYITHSIHNIKPTRSDCDTALASYKS-----GTLVSLGF-PPESCGYASVTDSEFLVIMITPHHVGVDDYR-----------GHWVDPLFVGGECDQSYCDTIHNSSVWIPADQTKK-----------NICGQSFTPLTVTVAYDKTKEIAAGGIVFKSKYHSHMEGARTCRLSYCG---------RNGIKFPN----------GEWVSLDVKTRIQEKHLLPLFKECPAGTEVRS-------------------TLQSDGAQVLTSEIQRILDYSLCQNTWDKVERKEP-------LSPLDLSYLASKSP---GKGLAYTVI-------NGTLSFAHTRYVRMWIDGPVLKEPKGKRESPSGISSDI--WTQWFKYGDMEIGPNGLLKTAGGYKFPWHLIGMGIVDNELHELSE------------ANPLDHPQLP

General information: TITO was launched using: RESULT: Template: 4D6W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 73415 for 2965 contacts (24.8/contact) + 2D Compatibility (PS) -41515 + (NN) 483 + (LL) 8896 1D Compatibility (HY) -5600 + (ID) 3500 Total energy: 32179.0 ( 10.85 by residue) QMean score : 0.115

(partial model without unconserved sides chains): PDB file : Tito_4D6W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4D6W-query.scw PDB file : Tito_Scwrl_4D6W.pdb: