Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLLSKKSEYKTLSTVEHPQYIVFCDFDETYFPHTIDEQKQQDIYELEDYLEQKSKDGELIIGWVTGSSIESILDKMGRGKFRYFPHFIASDLGTEITYFSEHNFGQQDNKWNSRINEGFSKEKVEKLVKQLHENHN-ILL--NPQ-TQL-----GKSRYKH-NF--Y---YQEQDE--IN-----D--KKNLLAIEKIC-EEYGVSVNINRCNPLAGDPEDSYDVDFIPIGTGKNEIVTFMLEKYNLNTERAIAFGDSGNDVRMLQTVGNGYLLKNATQEAKNLHNL--ITDSEYSKGITNTLKKLIGS 3PGV Chain:A ((21-284)) ------------------YQVVASDLDGTLLSPDHFL-----TPYAKETLKLL-TARGINFVFATGRHYIDVGQIRDNLGI---RSYMITSNGARVHDS--DGQQIFA--------HNLDRDIAADLFEIVR-NDPKIVTNVYREDEWYMNRHR---FFKEAVFNYKLYEPGELDPQGISKVFFTCEDHEHLLPLEQAMNARWGDRVNV--------SFSTLTCLEVMAGGVSKGHALEAVAKMLGYTLSDCIAFGDGMNDAEMLSMAGKGCIMANAHQRLKDLHPELEVIGSNADDAVPRYLRKLYL-

General information: TITO was launched using: RESULT: Template: 3PGV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1246 -94340 -75.71 -406.64 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -75.71 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.428

(partial model without unconserved sides chains): PDB file : Tito_3PGV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PGV-query.scw PDB file : Tito_Scwrl_3PGV.pdb: