Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLEVKTISVEDTYEIRH---RILRPHQ---SIEQCKYKED-HAEGSFHLGVFYDGTLISIASFSPQSQPL---------LTEASAYRLRGMATLEGYRDQKAGSTLIKHAEHKLAE-SGVQAVWCNARHHVKGYYAKLGWKELGEPFD-IPGIGNHIVMYKTLRTSR 1CJW Chain:A ((5-164)) ANEFRCLTPEDAAGVFEIEREAFISVSGNCPLNLDEVQHFLTLCPELSLGWFVEGRLVAFIIGSLWDEERLTQESLALHRPRGHSAHLHALAVHRSFRQQGKGSVLLWRYLHHVGAQPAVRRAVLMCEDALVPFYQRFGFHPAGPCAIVVGSLT-FTEMHC------

General information: TITO was launched using: RESULT: Template: 1CJW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 631 -98832 -156.63 -696.00 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -156.63 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.543

(partial model without unconserved sides chains): PDB file : Tito_1CJW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1CJW-query.scw PDB file : Tito_Scwrl_1CJW.pdb: