Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLIILEGPDCCFKSTVAAKLSKELK---YPII--KGSSFEL---AKSG--N------E----KL-FE--H---FNK----LADEDNVIIDRFVYSNLVYAKKFKDYSILTERQLRFIEDKIKAKAK-VVYLHADPSVIKKRLRVRGDEYIEGKDIDSILELYREVMSNAGLHTYSWDTGQWSSDEIAKDIIFLVE 1NN5 Chain:A ((9-198)) GALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAK--ENF-SLDWCKQP-DVGLPKPDLVLFLQLQLADAAKR-----ERYENGAFQERALRCFHQLMKDTTLNWKMVDASK-SIEAVHEDIRVLS-

General information: TITO was launched using: RESULT: Template: 1NN5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 656 -20628 -31.44 -133.94 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -31.44 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.455

(partial model without unconserved sides chains): PDB file : Tito_1NN5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1NN5-query.scw PDB file : Tito_Scwrl_1NN5.pdb: