Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSMAYEEYMRQLVVPMRRELTGAGFEELTTAEEVENFME--KAEGTTLVVVNSVCGCAA-GLARPAATQAVLQNDKTPDNTVTVFAGQDKEATAKMREYFTGQEPSSPSMALLKGKEVVHFIPRHEIEGHDMEEIMKNLTAAFDAHC 1EP7 Chain:A ((5-109)) -------------------------IVIDSKAAWDAQLAKGKEEHKPIVVDFTATWCGPCKMIAPLFETLSND---YAGK--VIFLKVDVDAVAAVAEAAG--ITAMPTFHVYKDGVKAD-----DLVGASQDKLKALVAKH-----

General information: TITO was launched using: RESULT: Template: 1EP7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 424 -4187 -9.88 -41.05 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -9.88 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.549

(partial model without unconserved sides chains): PDB file : Tito_1EP7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EP7-query.scw PDB file : Tito_Scwrl_1EP7.pdb: