Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMPRTIIEKIWDQHIVK-HG-EGKPDLLYIDLHLIHEVTSPQAFEGLRQKGRKVRRPQNTFATMDHNIPTVNRFEIKDEVAKRQVTALERNC-EEFGVRLADLHSVDQGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRPKTLEVRVDGTLQKGVTAKDVILAV----IG--KYG------VKFGTGYVIEYTGEVFRNMTMDERMTVCNMSIEAGARAGLIAPD-EVTFEYCKNR----------KYT--PK----GEEFDKAVEEWKALRTDPGAVYDKSIVLDGNKI-SPMVTWGINPGMVLPVDSEVPAPESFSAEDDKKEAIRAYEYMGLTPHQKIEDIKVEHVFIGSCTNSRMTDLRQAADMIKGKKVADSVRAIVVPGSQSVKLQAEKEGLDQIFLEAGFEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGHFVDVRKFYQEKTVV 1L5J Chain:A ((379-828)) DRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPV-----DVNTH-HTLPDFIMNRGGVSL-RPG---DGVIHSWLNR--MLLPDTVGTGGDSHTRFPIG---ISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIE--GLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPILCAPNDPDD-------------------------------ARPLSAVQGEKIDEVFIGSCMT-NIGHFRAAGKLLDAHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQ-ARVADGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQT-----

General information: TITO was launched using: RESULT: Template: 1L5J.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2412 12905 5.35 30.95 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 5.35 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.405

(partial model without unconserved sides chains): PDB file : Tito_1L5J.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L5J-query.scw PDB file : Tito_Scwrl_1L5J.pdb: