Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVYHFVGIKGTGMSPLAQILHDNGYTVQGSDIEKFIFTQTALEKRNITIL-PFSAEN-IKPGMTVIAGNAFPDTHPEIEKAMSEGIPVIRYHKFLGDYMK-KFTSVAVTGAHGKTSTTGLLAHVIQNAKP-TSFLIGDGT---GQ-------------GN--------E-NSEYFVFEACEYRRH-------FLSYQPDYAIMTNIDFDHPDYFSSIDDVFDAFQEMALQVNK--GIIACGDDEHLPKIHAN-----V---PVVYYGTGEENDFQARNIVKSTEGTTFDVFVRN--TFYDTFYIPAYGHHNVLNSLAVIALCHYEEIDSSIIKHALKSFGGVKRRFNEKQ-LGDQVLIDDYAHHPTEIKVTIEAARQKYPDREIVAVFQPHTFTRTQQFLDE-FAESLSGADCVYLCDIFGSARENAGK-LTIGDLQGKIH-NAKLI--EEDDTSVL--KAHDKAVLIFMGAGDIQKYMRAYENVMA 3HN7 Chain:A ((0-498)) GMHIHILGICGTFMGSLALLARALGHTVTGSDANIYPPMSTQLEQAGVTIEEGYLIAHLQPAPDLVVVGNAMKRGMDVIEYMLDTGLRYTSGPQFLSEQVLQSRHVIAVAGTHGKTTTTTMLAWILHYAGIDAGFLIGGVPLVNTTDTNLQQVFAHSSYLGTEKDDSDNSVNTGYFVIEADEYDSAFFDKRSKFVHYRPRTAILNNLEFD------DLDAIQTQFHHMVRMIPSTGKIIMPAATISLEDTLAKGVWTPIWRTSVID----NSSDWQAELIS--ADGSQFTVSFNDNKEATALVNWSMSGLHNVNNALVAIAAAYNIGVSVKTACAALSAFAGIKRRMELIGDVNDILVFDDFAHHPTAITTTLDGAKKKLADRRLWAIIEPRSNTMKMGIHQDSLAQSATLADHTLWYEPTG-LEWGLKEVIDNATIANPSIGSQQVLSSVDDIIKHICTHAKAGDAIVIMSNGGFEGIHQRLLTAL-

General information: TITO was launched using: RESULT: Template: 3HN7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2428 -42891 -17.66 -102.61 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -17.66 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.480

(partial model without unconserved sides chains): PDB file : Tito_3HN7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HN7-query.scw PDB file : Tito_Scwrl_3HN7.pdb: