Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDMKHTLLEALGIEIVENTAERCVAVMPVDHRTVQPFGYLHGGASVALAETAASAGAQNLIDHTTQACVGLEINANHLKSVKEGTVKAIAEPVHIGRTTIVYHIHIYDEQERLICISRCTLAVIKK 4YBV Chain:A ((2-120)) ---TH-LLETFEMSIDHQEDGLVVISMPVTDKVKAPFGYLHGGASIALGETACSLGSANLIDTTKFIPLGLEMNANHIHSAKDGRVTATAEIIHRGKSTHVWDIKIKNDKEQLITVMRGTVAI---

General information: TITO was launched using: RESULT: Template: 4YBV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 614 -87271 -142.13 -733.37 target 2D structure prediction score : 0.41 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -142.13 2D Compatibility (Sec. Struct. Predict.) : 0.41 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.531

(partial model without unconserved sides chains): PDB file : Tito_4YBV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YBV-query.scw PDB file : Tito_Scwrl_4YBV.pdb: