Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQHQLDDAEQLAFAGLLGTP-IGHPAAIALADDAPIITPINSEFGKANRWHTDVTFAANYPAASVLRAVSLPSYGGSTLWANTAAAYAELPEPLKCLTENLWALHTNRYDYVTTKPLTAAQRA-FRQVFEKPDFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSHESRVLFEVLQRRITMPENTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTLMGDVPVDVYGQASRVISGAPMEIAG 4Y0E Chain:E ((37-326)) ----ITVEKLGEHIGARVNGIELRGDLSADRVEAIRLALAINKVLVFTEQHHLDDAGQYAFARLLGEPTLPHPTVRSHGTEL-----LNLE-GAANGWHTDVTFVDRIPKASVLRPVTLPSYGGATTWASTVAAYEQLPKPLRSLVDDLWATHTNL--------------AAYYTEFTSSRYETVHPVVRVHPETGERSLLLGQFVKSFQDLPSAEFASLFQLLQARITKLENTFRWNWRLGDVAIWDNRATQHYGIADFGEQQRELHRVTLAGDVPVDVHGRRSQILLGDASHYSG

General information: TITO was launched using: RESULT: Template: 4Y0E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -101962 for 2252 contacts (-45.3/contact) + 2D Compatibility (PS) -29327 + (NN) -16058 + (LL) 1736 1D Compatibility (HY) -23200 + (ID) 7700 Total energy: -176511.0 ( -78.38 by residue) QMean score : 0.541

(partial model without unconserved sides chains): PDB file : Tito_4Y0E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Y0E-query.scw PDB file : Tito_Scwrl_4Y0E.pdb: