Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)



Input alignment information:
Query sequence-------------MITFLPIIFSILIVVIFVIGNFANGFIALVN---------SIEWVKRQKISFVDQILTALAVSRVGLLWVLLLHWYATQLNPAFYSVEVRITAYNVWAVTNHF---SSWLAT------------------SLSMFYLLRIANF-SNLIFLRI---KRRVKSVVLVILLGPLLFLVCHLFVINMD----ETVWTKEYEGNVT----WKIKLRSAMYHSN--------MTLTMLANFVPLTLTLISFLL----------LICSLCKHL--KKMQLHGKGSQ-------------------DPSTKVHIKALQTVTSFLLLCAIYFLSMIISVCNFGRLEKQPVFMFC-------QAIIFSYPSTHPFILIL---GNKKLKQIFLSVLRHVRYWVKDR--SLRLHRFTRGALCVF------------------------------------
2I2X Chain:A ((3-461))AKRYTSMAYANADEMTFGVSKYPVKAGLDLEIG--AGYTIPEINYAPRPEAGASKEKLIKEYERITTDVMERMVQVGFPAIILETEHVQQMSNNPSWGAEVAHAQKTIMEKYHDEYGIKCALRHTIGDIRENREFLQLRGDKYSVFLEAFEQCAENGADLLSVESMGGKEVFDYAVLRNDIPGLLYSIGCLGSIDMELIWTDISKIAKKTGTISAGDTDCAQANTAMFIGGGLLNKNLAHTIAVIARAISAPRSLVAYEAGAVGPGKDCGYENIIVKAITGMPMTMEGKTSTCAHSDVMGNLVMQCCDCWSNESVEYHGEFGGTTVQCWSETLAYDCALMNTALETKNDKVLRDLMMLSDRYRDPQAYMLAYDNAYRVGQSIVKDGDNIYLRAKNAAIECCNIIEEGAAGKLELSRFETKALADAKAALEALPDDMDKFMDDCLTKYKSEVKVFKPENYGF


General information:
TITO was launched using:
RESULT:

Template: 2I2X.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
3D Compatibility (PKB) -344340 for 2564 contacts (-134.3/contact) +
2D Compatibility (PS) -33141 + (NN) -5869 + (LL) 52
1D Compatibility (HY) -1600 + (ID) 2500
Total energy: -387398.0 ( -151.09 by residue)
QMean score : 0.198

(partial model without unconserved sides chains):
PDB file : Tito_2I2X.pdb:





(Unconserved sides chains are recalculated) :
Sequence: align-2I2X-query.scw
PDB file : Tito_Scwrl_2I2X.pdb: