Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSASIHGIIGYTITPFAADGGLDLPALGRSIERLIDGGVHAIAPLGSTGEGAYLSDPEWDEVVDFTLKTVAHRVPTIVSVSDLTTAKTVRRAQFAESLGAEAVMVLPISYWKLNEAEVFQHYRAVGEAIGVPVMLYNNPGTSGIDMSVELILRIVREVDNVTMVKESTGDIQRMHK-LRLLGEGRVPFYNGCNPLALEAFVAGAKGWCSAAPNLIPTLNGQLYQAVLDGDLEKARALFYRQLPLLDFILRRGLPTTIKAGLGLSGLEVGAPRLPVQALDTEGCRYLQGLLEELR 3S8H Chain:B ((2-273)) ----IAGSMVALVTPFDAQGRLDWDSLAKLVDFHLQDGTNAIVAVGTTGESATLDVEEHIQVVRRVVDQVKGRIPVIAGTGANSTREAVALTEAAKSGGADACLLVTPYYNKPTQEGMYQHFRHIAEAVAIPQILYNVPGRTSCDMLPETVERLSK-VPNIIGIKEATGDLQRAKEVIERVGKDFL-VYSGDDATAVELMLLGGKGNISVTANVAPRAMSDLCAAAMRGDAAAARAINDRLMPLHKALFIESNPIPVKWALHEMGLIPEGIRLPLTWLSPHCHDPLRQAMRQTG

General information: TITO was launched using: RESULT: Template: 3S8H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -190943 for 2431 contacts (-78.5/contact) + 2D Compatibility (PS) -29572 + (NN) -13791 + (LL) 260 1D Compatibility (HY) -11200 + (ID) 4450 Total energy: -249696.0 ( -102.71 by residue) QMean score : 0.587

(partial model without unconserved sides chains): PDB file : Tito_3S8H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3S8H-query.scw PDB file : Tito_Scwrl_3S8H.pdb: