Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLISWNIDSLNAALTSESTRALMSRQVIDTLVAEDADIIAIQETKLSAKGPTKKHLEVLETYFPEYDLVWRSSVEPARKGYAGTMFLYRKGLNPI-VSFPEIDAPTTMDNEGRIITLELENCYITQVYTPNAGDGLKRLGDRQIWDIKYAEYLATLDSQKPVLATGDYNVAHKEIDLANPSSNRRSAGFTDEERQGFTNLL-AKGFTDTFRYLHGDVPNVYSWWAQRSRTSKINNTGWRIDYWLTSNRVADKITKSEMIHSGDRQDHTPIILEIEL 2ISI Chain:C ((61-317)) LKICSWNVDGL---------RAWIKKKGLDWVKEEAPDILCLQETKCS-ENKLPAELQELPGLSHQY---WSAP-----EGYSGVGLLSRQ--CPLKVSYGIGD--EEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYM-MNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

General information: TITO was launched using: RESULT: Template: 2ISI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -85100 for 2171 contacts (-39.2/contact) + 2D Compatibility (PS) -27222 + (NN) -10055 + (LL) 1352 1D Compatibility (HY) -19600 + (ID) 5050 Total energy: -145675.0 ( -67.10 by residue) QMean score : 0.442

(partial model without unconserved sides chains): PDB file : Tito_2ISI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ISI-query.scw PDB file : Tito_Scwrl_2ISI.pdb: