Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAHTNTQLSQWLESKVGQTLDIRKGELTHDEEISDLDQIVLHL---QKVAIRSTNHPDDYVA-----KEELVLEGEGTTFTEDGNVPLPQN-AYEIPLLGELHIHQENEGLKVVTDRAVYTIDIQHS 4DY5 Chain:A ((1-111)) -----TGKNVNVEFDKGQNSARYSGVIKG----YDYDTYNFQARKGQKVHVSISNEGADTYLFGPGISDSVDLSRYSSELDGNGQYTLPASGKYELKVLQTRNEARKNK-------AKKYSVNIQIK

General information: TITO was launched using: RESULT: Template: 4DY5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 463 -28698 -61.98 -281.35 target 2D structure prediction score : 0.38 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -61.98 2D Compatibility (Sec. Struct. Predict.) : 0.38 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.282

(partial model without unconserved sides chains): PDB file : Tito_4DY5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DY5-query.scw PDB file : Tito_Scwrl_4DY5.pdb: