Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGQKFHKLNSKYGIIDYPILLKDLESIIQEFPKSERKFYEYAIKALKKEVGKKEKILHMTS--ADPKLTKFGFMVITEKKLLFVTMKGGFFGGADTEVVEFK-------SIKEV--DFDIAPNPLGMATMQLGILHLKIKGKLGMSSKRTIRNIDEHSLDKIVAILREQTK 1C06 Chain:A ((1-159)) -----------MKLSEYGLQLQEKQKLRHMYGVNERQFRKTFEEAGKMPGKHGENFMILLESRLDNLVYRLGLARTRRQARQLVTHGHILVDGSRVNIPSYRVKPGQTIAVREKSRNLQVIKEALEANNYIPDYLSFDPEKMEGTYTRLPERSELPAEINE-ALIVEFYSR

General information: TITO was launched using: RESULT: Template: 1C06.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 586 7393 12.62 49.95 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 12.62 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.150

(partial model without unconserved sides chains): PDB file : Tito_1C06.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1C06-query.scw PDB file : Tito_Scwrl_1C06.pdb: