Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDKTMKDIQAEVDRYIGQFKEGYFSPLAMMARLTEELGELAREVNHRYGEKPKKATEDDKSMEEEIGDVLFVLVCLANSLDISLEEAHDRVMHKFNTRDKDRWTRKEEGK 2Q5Z Chain:A ((20-112)) --HMKLSELQSHIKEFDYAPE----QSEHYFFKLIEEVGELSESIRKGKSGQPT-LDELKGSVAEELYDVLYYVCALANIHGVNLEKTRELKEVLNKVKY-----------

General information: TITO was launched using: RESULT: Template: 2Q5Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 221 -7496 -33.92 -80.60 target 2D structure prediction score : 0.83 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -33.92 2D Compatibility (Sec. Struct. Predict.) : 0.83 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.383

(partial model without unconserved sides chains): PDB file : Tito_2Q5Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Q5Z-query.scw PDB file : Tito_Scwrl_2Q5Z.pdb: