Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYAIIKTGGKQIKVEEGQTVYIEKLAAEAGETVTFEDVLFVGGDNVKVGNPTVEGATVTAKVEKQGRAKKITVFRYKPKKNVHKKQGHRQPYTKVTIEKINA 5DM6 Chain:O ((5-98)) ----IQTGGKQYRVSEGDVIRVESLQGEAGDKVELK-ALFVGGEQTVFGED-AGKYTVQAEVVEHGRGKKIYIRKYKSGVQYRRRTGHRQNFTAIKILGI--

General information: TITO was launched using: RESULT: Template: 5DM6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain O - contact count / total energy / energy per contact / energy per residue : 319 -24932 -78.16 -265.23 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain O : 0.79 3D Compatibility (PKB) : -78.16 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.360

(partial model without unconserved sides chains): PDB file : Tito_5DM6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DM6-query.scw PDB file : Tito_Scwrl_5DM6.pdb: